Glibenclamide GlibenclamideRs 2,000 / KgUsage: ClinicalChemical Name: MethoxybenzamideCAS Number: 10238-21-8Chemical Formula: C23H28ClN3O5SMolecular Mass: 494.01 g/molTherapeutic Category: Antidiabetic Usage: ClinicalChemical Name: MethoxybenzamideCAS Number: 10238-21-8Chemical Formula: C23H28ClN3O5SMolecular Mass: 494.01 g/molTherapeutic Category: Antidiabetic We are leading manufacturer and exporter of Glibenclamide and our product is made up of good quality.Product NameGlibenclamide BP/EP/USPChemical Name5-chloro-N-(4-[N-(cyclohexylcarbamoyl)sulfamoyl]phenethyl)-2-methoxybenzamideCAS Number10238-21-8Chemical FormulaC23H28ClN3O5SMolecular Mass494.01 g/molTherapeutic CategoryAntidiabeticInstructions of Glibenclamide :TestSpecificationDescriptionWhite or almost white crystalline powderSolubilityPractically insoluble in water, Sparingly soluble in methylene chloride, slightly soluble in ethanol (95%) and in methanol.IdentificationA) Melting PointB) By UVC) By IRD) By TLCE) Chemical test(A) Not less Than 169°C and not more than174°C (B) Examined between 230nm and 350nm the solution shows an absorption maximum at 300 nm and a less intense maximum at 275nm. the Specific absorbance at the maxima are 61 to 65 and 27 to 32 respectively,(C) The infra-red absorption spectrum of test substances should be Concordant with the spectrum of Glibenclamide Standard.(D) The principal spot obtained with the test solution should be similar in Position and size to the prinicipal spot obtained in the chromatogram Obtained with the reference solution.(E) The solution is colourless and shows blue Fluorescence in ultraviolet light at 365 nm. Colour changes to deep yellow and, after abut 20 minutes develops a brownish tinge with Choral hydrate.Heavy metalNMT 20ppmSulphated AshNMT 0.1 %w/wRelated substances by HPLCImpurity A NMT 0.5 %Impurity B NMT 0.5 %Any other Impurity NMT 0.2 %Two such Peak NMT 0.1 %Total of other impurities NMT 0.5 %Loss on drying (at 105°C for three Hours)NMT 1.0%w/wAssay by Titrimetry on dried basisNLT 99.0%w/w and NMT equivalent of 101.0%w/wResidual Solvent by HSGCMethanol NMT 3000 ppmAcetone NMT 5000 ppmEthylene dichloride NMT 5 ppmknow more6735375712Get Best PriceCall Now
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