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Naloxone Hydrochloride Injections

Naloxone Hydrochloride Injections

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Naloxone Hydrochloride Injections
Being pioneers in the medical industry, we bring forth hygienically formulated array of Yashinalox (Naloxone HCl) that is an opioid antagonist that functions competitively...

Being pioneers in the medical industry, we bring forth hygienically formulated array of Yashinalox (Naloxone HCl) that is an opioid antagonist that functions competitively at opioid receptors. It is an effective antagonist of opioids that possess agonist or mixed agonist-antagonist activity although larger doses may be needed for compounds with the latter activity. It is a special vnarcotic drug used to reverse the effects of other narcotic drugs that are used in the surgical operations or to treat acute pain. Yashinalox inj constitutes naloxone hydrochloride USP 0.4mg in definite quantity and may also be used treat narcotic drug overdose or to diagnose narcotic drug addiction.



Composition:
  • Each ml contains: naloxone hydrochloride USP 0.4mg, water for injection USP q. s.
Catogery:
  • Opioid receptor antagonist
Molecular formula:
  • C19H21NO4 .HCL
Molecular weight:
  • 363.84
Pharmacokinetics:
  • Naloxone is absorbed from the gastrointestinal tract but it is subject to considerable first-pass metabolism. It is metabolized in the liver, mainly by glucuronide, and excreted in the urine. It has a plasma half-life of about 1 hour after parenteral administration. Naloxone crosses the placenta.
Indications:
  • It is used to reverse opioid central depression, including respiratory depression, induced by natural or synthetic opioids in the treatment of known or suspected opioid overdosage, postoperatively after the use of opioids during surgery, and in neonates after the administration of opioid analgesics to the mother during labour.
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Yashica Pharmaceuticals Private Limited