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Veterinary Formulations

Fipronil Spray (0.25% w/v 100 mL)

Fipronil Spray (0.25% w/v 100 mL)

Approx. Rs 100 / Pack


The Fipronil spray is used for effective treatment and prevention of all life stages of ectoparasites in cats and dogs.

The spray poses no harmful effect on the fur of animals.

It stays on for longer duration and offer effective protection for longer time.

It is effective on tick, flea and lice in dogs and cats.


Composition:
  • Each mL contains :
    • Fipronil : 0.25% w/v
    • Excipients : q. s.
PHARMACOLOGY :
  • Mechanism of Action:Fipronil is a new generation broad-spectrum ectoparasiticide belonging to phenylpyrazole class. Fipronil disrupts the insect's central nervous system by blocking the passage of chloride ions through the GABA receptor and glutamate receptor (GluCl). Fipronil acts by binding to an allosteric site of GABA receptors. Its neurotoxicity is selective, because the configuration of GABA receptors in mammals is different from insects.
INDICATIONS :
  • Fipronil spray is used for effective treatment and prevention of all life stages of ectoparasites like tick (including ticks responsible for tick fever), flea (flea allergy dermatitis) and lice in Dogs and Cats.
DOSAGE AND ADMINISTRATION :
  • Each trigger application of spray delivers 0.5 mL spray volume.
Direction for Use :
  • Hold the bottle in upright position. Ruffle the animal’s coat while applying spray mist to its body. In order to wet the coat down to the skin the following application rates are recommended for use:
  • For Short-haired animals (< 1.5cm) - A minimum of 3mL/Kg body weight (7.5mg of active material per Kg of body weight) i.e. 6 pump actions per Kg.
    • Example :
    • For dogs under 12 Kg weight = 72 Pump actions
    • For dogs with 15 Kg weight = 90 Pump actions
    • For dogs with 30 Kg weight = 180 Pump actions
  • For Long-haired animals (> 1.5cm) - A minimum of 6mL/Kg body weight (15mg of active material per Kg of body weight) i.e. 12 pump actions per Kg.
    • Example :
    • For dogs under 12 Kg weight = 144 Pump actions
    • For dogs with 15 Kg weight = 180 Pump actions
    • For dogs with 30 Kg weight = 360 Pump actions
RESIDUAL ACTION:
  • Ticks : 1 month (3-5 week),
  • Fleas : 2 months (1-3 months)
  • This will depend on the parasite challenge in the animal's environment.
PRECAUTIONS :
  • Wear gloves during spraying.
  • Avoid spraying into eyes while spraying on face. To prevent spraying into eyes and to ensure proper coverage on head in nervous animals, puppies and kittens spray the solution onto the gloves first and then rub on face and other body parts of the pet.
  • Do not allow animal to lick the spray.
  • Do not bath or shampoo the animal for at least 2 days after Fipronil spray treatment.
  • Do not smoke, eat or drink during application.
  • Wash the hands after use.
  • Spray in well-ventilated area.
  • Keep sprayed animals away from source of heat until animal gets dry.
  • Do not spray directly on the area of damaged skin.
  • Do not apply to puppies kittens below the age of eight weeks.

Bithionol Sulfoxide Bolus 2g

Bithionol Sulfoxide Bolus 2g

Approx. Rs 500 / Pack


Bithionol Sulfoxide is an active anthelmintic for the treatment of fascioliosis and paramphistomosis, and has good activity against adult Oesophagostomum and some cestodes (Thysaniezia, Moniezia).

It is also acting as an intestinal disinfectant. It can be administered in pregnant and lactating females without any change of feeding.

 


Composition:
  • Each Bolus of 2.7g Contains :
    • Bithionol Sulfoxide : 2.0 g
    • Excipients : q. s.
TARGET SPECIES :
  • Cattle, sheep, goats, dogs, cats, and poultry animals
ROUT OF ADMINISTRATION :
  • Oral
INDICATIONS :
  • Bithionol indicated for the effective treatment and control of liver fluke (Fasciola hepatica), Oesophagostomum, Paramphistomum, Tapeworms (Moniezia), Thysaniezia ovilla in cattle, sheep and goats.
MECHANISM OF ACTION :
  • Bithionol interferes with the neuromuscular physiology of helminths /(the target species)/, impairs egg formation, and may cause the protective cuticle covering the worms to become defective. At the biochemical level, oxidative phosphorylation is inhibited, and the bithionol molecule can chelate iron so that it may inactivate iron-containing enzyme systems.
CONTRAINDICATIONS :
  • Preferably not to be administered to animals which have not been vaccinated against enterotoxaemia.
INCOMPATIBILITY WITH OTHER DRUGS OR SUBSTANCES :
  • Do not combine with other anthelmintics.
DOSAGE AND ADMINISTRATION :
  • For oral administration.
  • General Dose - Bithionol Sulfoxide 60mg/Kg
  • Dog, Cat, Sheep, Goat : 200mg/kg
  • : 200mg/kg Single dose
  • Chicken : 200mg/kg Twice within 4 days
  • Fowl, Goose : 600mg/kg as Single treatment.
  • Repeat treatment only on advice of your veterinarian.
WITHDRAWAL PERIOD :
  • Meat : 15 days
  • Milk : None
SIDE EFFECTS :
  • Mild and transitory diarrhoea may sometimes be observed.
PRESENTATION :
  • White coloured, 100 boli packed in HDPE jar along with pack insert.
STORAGE :
  • Store in well closed light resistant container in a cool and dry place below 30 C.

Fipronil Spot On Solution For Cats & Kittens (0.5 mL)

Fipronil Spot On Solution For Cats & Kittens (0.5 mL)

Approx. Rs 250 / Pack


The Fipronil Spot-on Solution For Cats & Kittens belongs to the family of phenylpyrazole and comes under the category of Insecticide-acaricide.

It serves as the spot on control and treatment of Flea Allergy Dermatitis in cats and kittens.



Composition:
  • Each pipette Contains :
    • Fipronil : 9.8% w/w
    • S-Methoprene : 8.8% w/w
    • Excipients : q. s.
CATEGORY :
  • Insecticide-acaricide
PHARMACODYNAMICS :
  • Fipronil is belonging to the family phenylpyrazole. It acts by interaction with complexes formed between the chloride channels and their ligands, especially the neurotransmitter GABA (gamma-amino butyric acid), thus blocking the transfer of chloride ions across cell membranes to levels pre and post synaptic. It thus causes uncontrolled activity on the central nervous system of insects and mites and causes their death. Fipronil kills fleas within 24 hours, ticks (Dermacentor variabilis, Rhipicephalus sanguineus, Ixodes scapularis, Ixodes ricinus, Haemaphysalis longicornis, Haemaphysalis flava and Haemaphysalis campanulata) and lice within 48 hours after application of the product.
    The S-Methoprene is a regulator of insect growth (ROI) of the class of similar juvenile hormone, it inhibits the development of immature stages of insects. Mimicking the action of the juvenile hormone, the compound causes impaired development and death of immature stages of fleas. The ovicidal activity of S-Methoprene applied to the cat results either from direct penetration into the shell flea eggs newly laid or its absorption through the cuticle of adult fleas. The S-Methoprene is also effective in preventing the development of larvae and pupae chip, prevents contamination of the habitat of cats treated with the immature stages of fleas.

 

Fipronil Spray (0.25% w/v 100 mL)

Fipronil Spray (0.25% w/v 100 mL)

Approx. Rs 250 / Pack


The Fipronil spray is used for effective treatment and prevention of all life stages of ectoparasites in cats and dogs.

The spray poses no harmful effect on the fur of animals.

It stays on for longer duration and offer effective protection for longer time.

It is effective on tick, flea and lice in dogs and cats.


Composition:
  • Each mL contains :
    • Fipronil : 0.25% w/v
    • Excipients : q. s.
PHARMACOLOGY :
  • Mechanism of Action:Fipronil is a new generation broad-spectrum ectoparasiticide belonging to phenylpyrazole class. Fipronil disrupts the insect's central nervous system by blocking the passage of chloride ions through the GABA receptor and glutamate receptor (GluCl). Fipronil acts by binding to an allosteric site of GABA receptors. Its neurotoxicity is selective, because the configuration of GABA receptors in mammals is different from insects.
INDICATIONS :
  • Fipronil spray is used for effective treatment and prevention of all life stages of ectoparasites like tick (including ticks responsible for tick fever), flea (flea allergy dermatitis) and lice in Dogs and Cats.
DOSAGE AND ADMINISTRATION :
  • Each trigger application of spray delivers 0.5 mL spray volume.
Direction for Use :
  • Hold the bottle in upright position. Ruffle the animal’s coat while applying spray mist to its body. In order to wet the coat down to the skin the following application rates are recommended for use:
  • For Short-haired animals (< 1.5cm) - A minimum of 3mL/Kg body weight (7.5mg of active material per Kg of body weight) i.e. 6 pump actions per Kg.
    • Example :
    • For dogs under 12 Kg weight = 72 Pump actions
    • For dogs with 15 Kg weight = 90 Pump actions
    • For dogs with 30 Kg weight = 180 Pump actions
  • For Long-haired animals (> 1.5cm) - A minimum of 6mL/Kg body weight (15mg of active material per Kg of body weight) i.e. 12 pump actions per Kg.
    • Example :
    • For dogs under 12 Kg weight = 144 Pump actions
    • For dogs with 15 Kg weight = 180 Pump actions
    • For dogs with 30 Kg weight = 360 Pump actions
RESIDUAL ACTION:
  • Ticks : 1 month (3-5 week),
  • Fleas : 2 months (1-3 months)
  • This will depend on the parasite challenge in the animal's environment.
PRECAUTIONS :
  • Wear gloves during spraying.
  • Avoid spraying into eyes while spraying on face. To prevent spraying into eyes and to ensure proper coverage on head in nervous animals, puppies and kittens spray the solution onto the gloves first and then rub on face and other body parts of the pet.
  • Do not allow animal to lick the spray.
  • Do not bath or shampoo the animal for at least 2 days after Fipronil spray treatment.
  • Do not smoke, eat or drink during application.
  • Wash the hands after use.
  • Spray in well-ventilated area.
  • Keep sprayed animals away from source of heat until animal gets dry.
  • Do not spray directly on the area of damaged skin.
  • Do not apply to puppies & kittens below the age of eight weeks.
SAFETY :
  • Fipronil spray is safe to use in dogs and cats with no toxic effects when used in recommended way. Fipronil spray is not absorbed by skin and stay on for longer duration to provide effective protection.

Veterinary Chemicals

Veterinary Chemicals

Approx. Rs 500 / Pack


We offer an extensive range of Veterinary Medicines.

The products are processed by experts with international standards using quality approved ingredients with the help of highly advance technology.

These tablets are available in varied packaging options.

Instructions:

 

Oxyclozanide

Oxyclozanide

We are leading manufacturer and exporter of Oxyclozanide and our product is made up of good quality.

Product NameOxyclozanide BP/EP/USP
Chemical Name2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide
CAS Number2277-92-1
Chemical FormulaC13H6Cl5NO3
Molecular Mass401.46 g/mol
Therapeutic CategoryAnthelmintic

Specification of Oxyclozanide :

TestSpecification
NatureA pale, cream colour odourless powder
SolubilitySlightly soluble in water, freely soluble in acetone, soluble in ethanol (96%),slightly soluble in chloroform
IdentificationAs per BP Vet
Melting PointAbout 208 ºC
Ionisable chlorineNMT 0.25%
Related substance by HPLC
A) Individual Impurity
B) Total Impurity

NMT 0.3%
NMT 1%
Loss on Drying (At 60ºC under vacuum)NMT 1% w/w
Moisture contentNMT 0.5%
Sulphated AshNMT 0.2% w/w
Assay (Dry Basis)NLT 98.00% NMT 101.00%

Closantel

Closantel

We are leading manufacturer and exporter of Closantel and our product is made up of good quality.

An anthelmintic used mostly in domestic animals, used as a dewormer for cattle, sheep, horse, pig, dog, camel etc.

It is highly effective against itch-mite, mange, fascioliasis, sheepnose fly, cowskin fly, fascioliasis, gastrointestinal nematode and demodicidosis etc.

Quinapyramine Chloride/Sulphate BP

Quinapyramine Chloride/Sulphate BP

We are leading manufacturer and exporter of Quinapyramine Chloride/Sulphate BP and our product is made up of good quality.

Product NameQuinapyramine Chloride/Sulphate BP/EP/USP
Chemical Name-
CAS Number23609-66-7
Chemical Formula-
Molecular Massg/mol
Therapeutic Category-

Instructions of Quinapyramine Chloride/Sulphate :

TestSpecification
DescriptionA white, cream coloured or very pale yellow crystalline powder, odourless with a bitter taste
SolubilitySoluble at 20°C in 2 parts of water almost in soluble in organic solvents.
Identificationa). To 5 ml of a 1 % w/v solution in water add 1ml of potassium ferricyanide solution: a yellow precipitate is formed
b). To 0.1gr add 0.2ml of fuming nitric acid. An immediate purple colour is produced
c) It melts at about 266°C with decomposition
d) Dissolve 0.1gr add 10 ml of water add 0.5ml of HCl, boil for 5 minutes cool and filter, the filtrate gives the reaction characteristic of sulphates.
Acidity as pHThe pH of 10 % w/v solution in CO2 Free water it is not below 2.5
ArsenicNMT 5 ppm
LeadNMT 10 ppm
Loss on dryingNMT 1.5 % w/w determined by drying to constant weight at 130°C
Sulphated ashNMT 0.2 %w/w
AssayNLT 98.0 % w/w and NMT 102.0 % w/w calculated with reference to the substance dried under the prescribed conditions.

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    Sanjay Totre

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    Yashica Pharmaceuticals Private Limited

    Syndicate, Thane, Maharashtra, India

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