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Drug Intermediates

API Intermediate

API Intermediate

We are leading manufacturer and exporter of API Intermediate and our product is made up of good quality.

As an organization, we are become reputed in short span of time in offering highly effective API Intermediate to our clients which are free from all sorts of impurities and is offered in bulk quantities to our clients. 


The intermediates are checked on well defined parameters before delivery process. We have an excellent range of this API Intermediate available with us.

Activated Charcoal Capsules

Activated Charcoal Capsules

Approx. Rs 100 / Pack


Activated charcoal is a potent natural treatment used to trap toxins and chemicals in the body, allowing them to be flushed out so the body doesn’t reabsorb them. One of the most popular activated charcoal uses is for the safe and effective treatment of poisoning and drug overdoses. It’s used in emergency trauma centers across the world. In addition, it’s used to reduce bloating and gas, lower cholesterol, treat bile flow problems safely during pregnancy, and even prevent hangovers.

Research shows that activated charcoal works better than stomach pumping (gastric lavage) in some situations.

 

TEST

SPECIFICATION AS PER USP

Description

Black hard gelation capsules, size “0”, containing black coloured granules.

Weight of 20 filled capsules

10.00 gm

Avg. wt. of Capsule

500 mg

Uniformity Of Weight

Within ± 7.5% Of Average Weight

Disintegration Time

NMT 30 Min In Water Medium At 37°C

Average net Content

400 ± 7.5%

Adsorptive power of Charcoal USP 260 mg

The difference between sample and blank titration is 0.7 ml.

Paracetamol Tablets

Paracetamol Tablets

Approx. Rs 120 / Pack


TEST

SPECIFICATION

Description

A white coloured, round shaped flat beveled edged, uncoated tablet with break line on one side and plain on other side.

Identification:

By IR

 

 

 

By Melting Point

By Colour Development

Should comply as per BP

The IR absorption spectrum of the residue of sample preparation should be concordant with the reference spectrum of the paracetamol

About 169° C

A violet colour should develop which does not turn red.

Uniformity of weight

± 5% of average weight

Average Weight

560.00 mg ± 3%

Thickness

3.80 mm (± 0.2 mm)

Diameter

12.70 mm (± 0.2 mm)

Disintegration time

NMT 15 minutes

Hardness

NLT 3 kg/cm2

Friability

NMT 1.0%

Dissolution

NLT 75%

Related Substances

Must comply as per BP

Assay

95.0% to 105.0% of LA

Vitamin K Injection

Vitamin K Injection

Approx. Rs 50 / Piece


We are leading manufacturer and exporter of Vitamin K Injection and our product is made up of good quality.

TEST

SPECIFICATION AS PER USP

Description

A golden yellow coloured solution

Identification

Complies

pH

5.0 to 7.5

Sterility testing

Complies as per BP

Volume Variation

NLT 1.0 ml

Assay:

Each ml contains: Phytomenadione BP…..10mg

 

90.0% to 115.0%

Hydrocortisone Sodium Succinate Injection

Hydrocortisone Sodium Succinate Injection

Approx. Rs 100 / Pack


We are leading manufacturer and exporter of Hydrocortisone Sodium Succinate Injection and our product is made up of good quality.

NAME OF PRODUCT : YASHICORT 500 (HYDROCORTISONE SODIUM SUCCINATE FOR INJECTION BP)
TESTSPECIFICATION AS PER USP
DescriptionA white powder along with water for injection.
Assay - Each mL contains:
Hydrocortisone Sodium Succinate 500 mg
90.0% to 110.0%

NAME OF PRODUCT : YASHICORT 250 (HYDROCORTISONE SODIUM SUCCINATE FOR INJECTION BP)
TESTSPECIFICATION AS PER USP
DescriptionA white powder along with water for injection.
Assay - Each mL contains:
Hydrocortisone Sodium Succinate 250 mg
90.0% to 110.0%

NAME OF PRODUCT : YASHICORT 750 (HYDROCORTISONE SODIUM SUCCINATE FOR INJECTION BP)
TESTSPECIFICATION AS PER USP
DescriptionA white powder along with water for injection.
Assay - Each mL contains:
Hydrocortisone Sodium Succinate 750 mg
90.0% to 110.0%

Ferrous Sulphate

Ferrous Sulphate

We are leading manufacturer and exporter of Ferrous Sulphate and our product is made up of good quality.

NAME OF PRODUCT : Ferrous Sulphate
CAS NO7720-78-7
FormulaFeSO4
DescriptionWhite Powder
Mol. Wt278.02
Solubility100% Water Soluble.
Clarity Of SolnShould Be Clear
Fe Content30-32%
PhBelow 3 Ph
Ferric0.01%
Assay99 % Min.
Packing50 Kg HDPE Bags.

Gripe Water

Gripe Water

Approx. Rs 50 / Pack


Test

In-House Specification

Description

A clear colourless liquid with characteristic odour

pH

5.0 – 6.0

Weight per mL

1.05 g/mL ± 0.05g/mL

Net filled Volume

121.0 mL ± 1 mL

Leak Test

Must comply

Microbial Test

 

Total Bacterial Count

NMT 1000 CFU/mL

Total Fungal Count

NMT 100 CFU/ mL

Pathogens:

 

E. coli

Should be Absent in 1.0 mL

Salmonella

Should be Absent in 10.0mL

P. aeruginosa

Should be Absent in 1.0 mL

S. aureus

Should be Absent in 1.0 mL

Gentamycin Injection

Gentamycin Injection

Approx. Rs 150 / Piece


This medication is used to prevent or treat a wide variety of bacterial infections. Gentamicinbelongs to a class of drugs known as aminoglycoside antibiotics. It works by stopping the growth of bacteria.

Anastrozole Intermediate

Anastrozole Intermediate

Anastrozole-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and postmenopausal women.

The severity of breast cancer is increased by estrogen, as hormones cause hyperplasia, and differentiation at estrogen receptor sites.

It works by inhibiting the synthesis of estrogen.

NAME OF PRODUCT : Anastrazole Intermediate
CAS NO120511-73-1
Structural FormulaC17H19N5
Molecular Weight293.37
AppearanceAn Off-White Color Crystalline Powder
UseIt Can Be Used To The Treatment Of Breast Cancer

Letrozole Intermediate

Letrozole Intermediate

Letrozole is a White to yellowish, crystalline powder and used as an oral non-steroidal aromatase inhibitor for the treatment of hormonally-responsive breast cancer after surgery.

NAME OF PRODUCT : Letrozole Intermediate
CAS NO112809-51-5
Chemical FormulaC17H11N5
MOL. WEIGHT285.303 G/Mol

Piperacillin & Tazobactam For Injections

Piperacillin & Tazobactam For Injections
Composition:
  • Each vial contains: piperacillin sodium USP, Eq. to piperacillin 4 g, tazobactam sodium, Eq. to tazobactam 0.5 g
Pharmacological classification:
  • Antibacterial
Mechanism of action:
  • Piperacillin, a broad spectrum, semisynthetic penicillin exerts bactericidal activity by inhibition of both septum and cell wall synthesis.
  • Tazobactam, a beta-lactam structurally related to penicillins, is an inhibitor of many beta- lactamases, which commonly cause resistance to penicillins and cephalosporins but it does not inhibit AmpC enzymes or metallo beta-lactamases.
  • Tazobactam extends the antibiotic spectrum of Piperacillin to include many beta-lactamase- producing bacteria that have acquired resistance to Piperacillin alone.
Indications and usage:
  • Yashipiptaz is used in the management of neutropenic patients with fever suspected to be due to a bacterial infection. Yashipiptaz is indicated for the treatment of the following infections in adults and children over 2 years of age
  • Adults and adolescents:
  • Severe pneumonia including hospital-acquired and ventilator-associated pneumonia
  • Complicated urinary tract infections (including pyelonephritis)
  • Complicated intra-abdominal infections
  • Complicated skin and soft tissue infections (including diabetic foot infections)
  • Children 2 to 12 years of age: Complicated intra-abdominal infections
Dosage and administration:
  • Yashipiptaz is administered by intravenous injection (over 30 minutes). The dose and frequency of Yashipiptaz depends on the severity and localization of the infection and expected pathogens.
  • Adult and adolescent patients:
  • For Infections: The usual dose of 4g piperacillin /0.5g tazobactam is given every eight hours.
  • For nosocomial pneumonia & bacterial infections in neutropenic patients: Recommended dose of 4g piperacillin /0.5g tazobactam is every six hours. This regimen may also be applicable to treat patients with other indicated infections when particularly severe.
  • For patients on haemodialysis, one additional dose of piperacillin/tazobactam 2g/0.25g should be administered following each dialysis period. No dose adjustment is required for the elderly with normal renal function or creatinine clearance values above 40 mL/min.
  • Children: YASHIPIPTAZ is not recommended for children below 2 years age.
  • Neutropenic children with fever suspected due to bacterial infections: 80mg
  • Piperacillin/10mg tazobactam per kg body weight, every six hours; not to exceed the maximum 4g /0.5g per dose over 30 minutes.
  • Complicated intra-abdominal infections: 100mg piperacillin/12.5mg tazobactam per kg body weight, every eight hours; not to exceed the maximum 4g/0.5g per dose over 30 minutes.
  • Creatinine Clearance = 50 mg/mL: 70mg piperacillin/8.75mg tazobactam per kg body weight, every eight hours.
  • For children on haemodialysis, one additional dose of 40mg piperacillin /5mg tazobactam per kg should be administered following each dialysis period.
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    Sanjay Totre

    (Managing Director)

    Yashica Pharmaceuticals Private Limited

    Syndicate, Thane, Maharashtra, India

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