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Ketorolac Tromethamine Injections

Ketorolac Tromethamine Injections

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Ketorolac Tromethamine Injections
Good health being the prime concern, we bring forth hygienic collection of Yashiketin that is an analgesic and antipyretic medicine. This is effective in nature and brings...

Good health being the prime concern, we bring forth hygienic collection of Yashiketin that is an analgesic and antipyretic medicine. This is effective in nature and brings down the high fever into normal. They are used as pain relievers without causing anesthesia. We offer them in different doses and get readily dissolved in blood stream. Each injection constitutes 30 mg per mL of Ketorolac Tromethamine that is a member of pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs).



Composition:
  • Each ml contains: ketorolac tromethamine USP 30 mg, excipients q. s.
Category:
  • Analgesic and antipyretic. Ketorolac Tromethamine is a member of the pyrrolo-pyrrole group of non-steroidal anti-inflammatory drugs (NSAIDs).
Indication:
  • Yashiketin injection is indicated for the short-term ( ≤ 5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting. Ketorolac tromethamine is not indicated for use in pediatric patients and it is NOT indicated for minor or chronic painful conditions. Increasing the dose of ketorolac tromethamine beyond the label recommendations will not provide better efficacy but will increase the risk of developing serious adverse events.
Dosage and administration:
  • Multiple-dose treatment (IV / IM) in adult’s patients < 65 years of age: The recommended dose is 30 mg ketorolac tromethamine injection every 6 hours. The maximum daily dose should not exceed 120 mg.
  • Single-dose treatments (IV / IM) in adults patients ≥ 65 years of age or renally impaired and/or less than 50 kg (110 lbs) of body weight: One dose of 15 to 30 mg.
Pharmacological action:
  • Ketorolac tromethamine is a non-steroidal anti-inflammatory drug (NSAID) that exhibits analgesic activity in animal models. Ketorolac tromethamine inhibits synthesis of prostaglandins and may be considered a peripherally acting analgesic. The biological activity of ketorolac tromethamine is associated with the S-form. Ketorolac tromethamine possesses no sedative or anxiolytic properties. The peak analgesic effect of ketorolac tromethamine occurs within 2 to 3 hours.
Adverse reactions:
  • Administration of Ketorolac Tromethamine Injections may cause adverse reactions as G.I. ulceration, bleeding and perforation, nausea, dyspepsia, gastrointestinal pain, diarrhea, constipation, flatulence, gastrointestinal fullness, vomiting, stomatitis, gastritis, rectal bleeding, eructation, anorexia, increased appetite, postoperative bleeding, acute renal failure, liver failure, edema, hypertension, pruritus, rash, purpura, headache, drowsiness, dizziness, sweating, tremors, abnormal dreams, hallucinations, euphoria, extrapyramidal symptoms, vertigo, paresthesia, depression, insomnia, nervousness, excessive thirst, dry mouth, abnormal thinking, inability to concentrate, hyperkinesis, stupor, weight gain, fever, infections, asthenia, palpitation, pallor, syncope, urticaria.
Warnings:
  • Yashiketin injection is a non-steroidal anti-inflammatory drug (NSAID) and should not be used to exceed more than 5 days in adults.

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Yashica Pharmaceuticals Private Limited